Before he died, Pasteur instructed his family not to release some 10,000 pages of lab notes after his death. Not until 1975, after the death of his grandson, were these "secret" notes finally made public. An historian from Princeton, Professor Geison made a thorough study of the lab notes. He presented his findings in an address to The American Association for the Advancement of Science in Boston in 1993.
Dr. Geison's conclusions: Pasteur published much fraudulent data and was guilty of many counts of "scientific misconduct," violating rules of medicine, science, and ethics.
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Before he died, Pasteur instructed his family not to release 10,000 pages of lab notes after his death. It is only after the death of his grandson in 1975 that Pasteur's secret notes were made public. Professor Gerald Geison, a science historian from Princeton University, made a thorough study of the notes and compared them with Pasteur's publications. He presented his findings in 1993 during a congress of the American Association for the Advancement of Science in Boston. This re-evaluation made him conclude that Pasteur committed scientific misconduct. He violated the medical, ethical and scientific rules and published fraudulent data.
For example, contrary to what Pasteur published, he never tested his anti-rabies vaccine on animals before he started experimenting on humans. The vaccine Pasteur used during his famous "antrax experiment" on sheep was - contrary to his claim - not his own vaccine. He stole it from a colleague, Toussaint. (Toussaint died a few months later after a nervous breakdown.) According to Geison, money was the primary motivation for Pasteur's misconduct.
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The real story behind Pasteur`s rabies vaccine did not emerge until over a hundred years later. Pasteur had kept secret laboratory notebooks of his work, but had decreed that his family was not to show these to anyone. In 1964, his last surviving grandson donated the documents to the Biblioteque Nationale, in Paris. A decade later, limited access to Pasteur`s hand-written notes was granted to a few historians - one of whom was Gerald Gelson. In 1993, at an AAAS Annual Meeting in Boston, America, Gelson revealed that Pasteur had tried his rabies vaccine on two patients with advanced sysmptoms of rabies - before he had tested the accine in symptomatic animals. The information presented showed that, in 1885, two boys were inoculated with the vaccine based on virus grown in the spines of rabbits - but Pasteur had not subjected this to experiments on animals. Of subsequent animal experiments, Gelson pointed out "Even his [animal] experiments trying to prevent rabies were inconclusive at the time"(147).
With the introduction of Pasteur`s rabies vaccine, it was claimed that of the first 350 human patients treated only one died(157) - but, in 1886, of 2,671 vaccinated 25 died(156). A year later, 1,778 people were given Pasteur`s rabies vaccine(157).The results were declared a "success" and made Pasteur world famous(15
- but in the first three years of vaccination -
1886 to 1889, the average death-rate from rabies was 36 per annum - whereas prior to its introduction - 1850 to 1872 - the average death-rate from rabies was 30 per annum(159) - i.e. mortality was lower before the introduction of vaccination. With a death following inoculation in 1887 at the Pasteur Institute in Paris, Michel Peter, a French professor, declared that Pasteur`s method was not only useless but dangerous(152). He repeated this assertion in a French medical journal in 1890, declaring "I have said, repeatedly, and professed, that the inoculation - pretended to be anti-rabic - of M Pasteur are in principle nonsense, and in practice would be deceptive"(161).
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Originally Posted by Candiru
